Neuropathology and pathogenesis of diabetic autonomic neuropathy

RE Schmidt - International review of neurobiology, 2002 - Elsevier
Autonomic neuropathy is a significant complication of diabetes resulting in increased patient
morbidity and mortality. A number of studies, which have shown correspondence between
neuropathologic findings in experimental animals and human subjects, have demonstrated
that axonal and dendritic pathology in sympathetic ganglia in the absence of significant
neuron loss represents a neuropathologic hallmark of diabetic autonomic neuropathy. A
recurring theme in sympathetic ganglia, as well as in the postganglionic autonomic …