[HTML][HTML] Helper T cell differentiation enters a new era: le roi est mort; vive le roi!
In the dark ages of T cell biology, we considered two fates for differentiated CD4+ T cells: T
helper (Th) 1 and Th2 cells. Now we know that the reality is much more complex and
interesting. The newest Th cell subset produces the cytokine IL-17. New evidence shows
that the IL-17–related cytokine IL-25 is essential for Th2 responses in two infectious disease
models.
helper (Th) 1 and Th2 cells. Now we know that the reality is much more complex and
interesting. The newest Th cell subset produces the cytokine IL-17. New evidence shows
that the IL-17–related cytokine IL-25 is essential for Th2 responses in two infectious disease
models.
Abstract
In the dark ages of T cell biology, we considered two fates for differentiated CD4+ T cells: T helper (Th) 1 and Th2 cells. Now we know that the reality is much more complex and interesting. The newest Th cell subset produces the cytokine IL-17. New evidence shows that the IL-17–related cytokine IL-25 is essential for Th2 responses in two infectious disease models.
ncbi.nlm.nih.gov