Molecular Characterization of the Human Transmembrane Protein-tyrosine Phosphatase δ: EVIDENCE FOR TISSUE-SPECIFIC EXPRESSION OF ALTERNATIVE …
R Pulido, NX Krueger, C Serra-Pagès, H Saito… - Journal of Biological …, 1995 - ASBMB
Protein-tyrosine phosphatases (PTPases) play an essential role in the regulation of cell
activation, proliferation, and differentiation. A major subfamily of these enzymes is the
transmembrane-type PTPases that contain extracellular regions comprised of Ig-like and
fibronectin type III (FN-III)-like domains. Characterization of the human transmembrane
PTPase δ (HPTPδ) revealed the existence of multiple HPTPδ isoforms that vary in their
extracellular regions. The full-length HPTPδ isoform has an extracellular region containing …
activation, proliferation, and differentiation. A major subfamily of these enzymes is the
transmembrane-type PTPases that contain extracellular regions comprised of Ig-like and
fibronectin type III (FN-III)-like domains. Characterization of the human transmembrane
PTPase δ (HPTPδ) revealed the existence of multiple HPTPδ isoforms that vary in their
extracellular regions. The full-length HPTPδ isoform has an extracellular region containing …
