[HTML][HTML] The pgdA gene encodes for a peptidoglycanN-acetylglucosamine deacetylase in Streptococcus pneumoniae
Analytical work on the fractionation of the glycan strands of Streptococcus pneumoniae cell
wall has led to the observation that an unusually high proportion of hexosamine units (over
80% of the glucosamine and 10% of the muramic acid residues) was not N-acetylated,
explaining the resistance of the peptidoglycan to the hydrolytic action of lysozyme, a
muramidase that cleaves in the glycan backbone. A gene, pgdA, was identified as encoding
for the peptidoglycanN-acetylglucosamine deacetylaseA with amino acid sequence …
wall has led to the observation that an unusually high proportion of hexosamine units (over
80% of the glucosamine and 10% of the muramic acid residues) was not N-acetylated,
explaining the resistance of the peptidoglycan to the hydrolytic action of lysozyme, a
muramidase that cleaves in the glycan backbone. A gene, pgdA, was identified as encoding
for the peptidoglycanN-acetylglucosamine deacetylaseA with amino acid sequence …
