Epithelial-mesenchymal transition (EMT) is a highly conserved morphogenic process
defined by the loss of epithelial characteristics and the acquisition of a mesenchymal
phenotype. EMT is associated with increased aggressiveness, invasiveness, and metastatic
potential in carcinoma cells. To assess the contribution of extracellular vesicles following
EMT, we conducted a proteomic analysis of exosomes released from Madin-Darby canine
kidney (MDCK) cells, and MDCK cells transformed with oncogenic H-Ras (21D1 cells) …