[59] Oxidant-antioxidant status in human immunodeficiency virus infection

W Dröge, HP Eck, S Mihm - Methods in enzymology, 1994 - Elsevier
Publisher Summary The hallmarks of the immunopathology of human immunodeficiency
virus (HIV) infection are the selective and progressive CD4+ T cell depletion and the cellular
dysfunction, which is observed even prior to the depletion of CD4+ cells and which also
affects other immunologically relevant cells including CD8+ T cells and B cells. This chapter
summarizes data suggesting that the acquired immunodeficiency syndrome may be (at least
partly) the consequence of a virus-induced cysteine deficiency. Elevated plasma glutamate …