[HTML][HTML] Cytomegalovirus-associated CD4+ CD28null cells in NKG2D-dependent glomerular endothelial injury and kidney allograft dysfunction
S Shabir, H Smith, B Kaul, A Pachnio, S Jham… - American Journal of …, 2016 - Elsevier
Emerging data suggest that expansion of a circulating population of atypical, cytotoxic CD4+
T cells lacking costimulatory CD28 (CD4+ CD28 null cells) is associated with latent
cytomegalovirus (CMV) infection. The purpose of the current study was to increase the
understanding of the relevance of these cells in 100 unselected kidney transplant recipients
followed prospectively for a median of 54 months. Multicolor flow cytometry of peripheral
blood mononuclear cells before transplantation and serially posttransplantation was …
T cells lacking costimulatory CD28 (CD4+ CD28 null cells) is associated with latent
cytomegalovirus (CMV) infection. The purpose of the current study was to increase the
understanding of the relevance of these cells in 100 unselected kidney transplant recipients
followed prospectively for a median of 54 months. Multicolor flow cytometry of peripheral
blood mononuclear cells before transplantation and serially posttransplantation was …
