Monoclonal antibodies for prevention and treatment of COVID-19

M Marovich, JR Mascola, MS Cohen - Jama, 2020 - jamanetwork.com
The coronavirus disease 2019 (COVID-19) pandemic has created a worldwide crisis and
inspired an urgent search for prevention and treatment of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. Attention has focused on the development of
vaccines, new antiviral agents, and convalescent plasma infusions. Monoclonal antibodies
have received less attention even though neutralizing antibodies are a key component of
protective immunity for most viral diseases. Neutralizing monoclonal antibodies to SARS …