[HTML][HTML] Characterization of circulating APOL1 protein complexes in African Americans

A Weckerle, JA Snipes, D Cheng, AK Gebre… - Journal of lipid …, 2016 - ASBMB
APOL1 gene renal-risk variants are associated with nephropathy and CVD in African
Americans; however, little is known about the circulating APOL1 variant proteins which
reportedly bind to HDL. We examined whether APOL1 G1 and G2 renal-risk variant serum
concentrations or lipoprotein distributions differed from nonrisk G0 APOL1 in African
Americans without nephropathy. Serum APOL1 protein concentrations were similar
regardless of APOL1 genotype. In addition, serum APOL1 protein was bound to protein …