Developments in medicine have led to a significant increase in the average human lifespan.
This increase in aging is most readily apparent in the case of HIV where antiretroviral
therapy has shifted infection from a terminal to a chronic but manageable disease. Despite
this advance, patients suffer from co-morbidities best described as an accelerated aging
phenotype. A potential contributor is cellular senescence, an aging-associated growth
arrest, which has already been linked to other HIV co-morbidities such as lipodystrophies …