Elevated MIF-2 levels predict mortality in critically ill patients
J Pohl, UB Hendgen-Cotta, P Stock, P Luedike… - Journal of critical …, 2017 - Elsevier
Purpose D-dopachrome tautomerase (MIF-2 or DDT) is a member of the macrophage
migration inhibitory factor (MIF) superfamily and a close structural homolog to MIF.
Circulating MIF-2 has been described to be elevated in patients suffering from sepsis,
severe burn injury and after surgery. We sought to evaluate the prognostic value of MIF-2 in
critically ill patients. Methods A total of 72 patients were studied upon admission to the
medical intensive care unit (ICU). MIF and MIF-2 levels were assessed and compared to …
migration inhibitory factor (MIF) superfamily and a close structural homolog to MIF.
Circulating MIF-2 has been described to be elevated in patients suffering from sepsis,
severe burn injury and after surgery. We sought to evaluate the prognostic value of MIF-2 in
critically ill patients. Methods A total of 72 patients were studied upon admission to the
medical intensive care unit (ICU). MIF and MIF-2 levels were assessed and compared to …