Podocyte and parietal epithelial cell interactions in health and disease

T Al Hussain, H Al Mana, MH Hussein… - Advances in Anatomic …, 2017 - journals.lww.com
The glomerulus has 3 resident cells namely mesangial cells that produce the mesangial
matrix, endothelial cells that line the glomerular capillaries, and podocytes that cover the
outer surface of the glomerular basement membrane. Parietal epithelial cells (PrECs), which
line the Bowman's capsule are not part of the glomerular tuft but may have an important role
in the normal function of the glomerulus. A significant progress has been made in recent
years regarding our understanding of the role and function of these cells in normal kidney …