Endothelial cell injury in acute and chronic glomerular lesions in patients with IgA nephropathy

T Kusano, H Takano, D Kang, K Nagahama, M Aoki… - Human pathology, 2016 - Elsevier
Endothelial cell injury may contribute to the progression of various glomerular diseases. In
the present study, we examined glomerular capillary injury in acute and chronic glomerular
lesions in patients with Immunoglobulin A nephropathy (IgAN). We selected renal biopsy
samples of IgAN (n= 200), and glomerular capillary injury in the acute and chronic
glomerular lesions was assessed using immunohistochemistry for CD34 and electron
microscopy. We examined the correlations between acute and chronic glomerular lesions …