[HTML][HTML] Early ultrastructural changes in renal allografts: correlation with antibody-mediated rejection and transplant glomerulopathy
M Haas, J Mirocha - American Journal of Transplantation, 2011 - Elsevier
Transplant glomerulopathy (TG) is associated with antibody-mediated renal allograft
rejection (AMR) and reduced graft survival. Histologically, TG is typically seen> 1 year
posttransplantation. However, ultrastructural changes including glomerular endothelial
swelling, subendothelial widening and early glomerular basement membrane duplication
are associated with development of TG but appear much earlier. We examined the
specificity of these changes for AMR, and whether these are inevitably associated with …
rejection (AMR) and reduced graft survival. Histologically, TG is typically seen> 1 year
posttransplantation. However, ultrastructural changes including glomerular endothelial
swelling, subendothelial widening and early glomerular basement membrane duplication
are associated with development of TG but appear much earlier. We examined the
specificity of these changes for AMR, and whether these are inevitably associated with …