Regulatory T cells and IL-10 levels are reduced in patients with vulnerable coronary plaques

J George, S Schwartzenberg, D Medvedovsky… - Atherosclerosis, 2012 - Elsevier
BACKGROUND: Despite having a similar large extent of atherosclerotic coronary affliction,
some patients suffer of recurrent cardiac events, whereas others remain asymptomatic.
HYPOTHESIS: We hypothesized the existence of a systemic “signature” that could
distinguish “vulnerable” patients with preexisting coronary atherosclerosis from those having
similar risk factors and atheromatous burden, but no history of clinically evident plaque
rupture/erosion. METHODS: Twenty three patients who had at least two prior myocardial …