Frequency of naturally-occurring regulatory T cells is reduced in patients with ST-segment elevation myocardial infarction

G Sardella, L De Luca, V Francavilla, D Accapezzato… - Thrombosis research, 2007 - Elsevier
BACKGROUND: Naturally-occurring regulatory T cells (Treg) constitute a mature T-cell
population characterized phenotypically by co-expression of CD4 and CD25high surface
molecules. We investigated here the frequency of circulating Treg in patients presenting with
STEMI in comparison with subjects without coronary artery disease (CAD). The effect of
primary percutaneous coronary intervention (PCI) with implantation of a bare (BS) or
paclitaxel-eluting stent (PES) on peripheral Treg distribution was also examined …