Minimal change disease associated with durvalumab
MG Toda, K Fujii, A Kato, A Yoshifuji… - Kidney International …, 2021 - kireports.org
To the Editor: At present, minimal change disease (MCD) caused by PD-L1 inhibitors has
not been reported. We have reported the first case of MCD caused by a PD-L1 inhibitor,
durvalumab. A 75-year-old Asian man who developed nephrotic syndrome after 4 cycles of
durvalumab administration for nonÀsmall cell lung cancer (NSCLC) was diagnosed with
MCD by kidney biopsy. Complete remission (CR) was achieved soon after administration of
prednisolone (PSL)(see Supplementary Material, Case Presentation and Supplementary …
not been reported. We have reported the first case of MCD caused by a PD-L1 inhibitor,
durvalumab. A 75-year-old Asian man who developed nephrotic syndrome after 4 cycles of
durvalumab administration for nonÀsmall cell lung cancer (NSCLC) was diagnosed with
MCD by kidney biopsy. Complete remission (CR) was achieved soon after administration of
prednisolone (PSL)(see Supplementary Material, Case Presentation and Supplementary …