Epithelial plasticity versus EMT in kidney fibrosis
S Huang, K Susztak - Trends in molecular medicine, 2016 - cell.com
S Huang, K Susztak
Trends in molecular medicine, 2016•cell.comTen percent of the population worldwide suffers from chronic kidney disease (CKD),
characterized by fibrotic changes in the kidney. Fibrosis is associated with loss of epithelial
parenchyma, and accumulation of myofibroblasts, fibrillary collagen, and inflammatory cells.
Two recent papers highlight the critical role of Twist and Snai1 transcription factors in kidney
fibrosis.
characterized by fibrotic changes in the kidney. Fibrosis is associated with loss of epithelial
parenchyma, and accumulation of myofibroblasts, fibrillary collagen, and inflammatory cells.
Two recent papers highlight the critical role of Twist and Snai1 transcription factors in kidney
fibrosis.
Ten percent of the population worldwide suffers from chronic kidney disease (CKD), characterized by fibrotic changes in the kidney. Fibrosis is associated with loss of epithelial parenchyma, and accumulation of myofibroblasts, fibrillary collagen, and inflammatory cells. Two recent papers highlight the critical role of Twist and Snai1 transcription factors in kidney fibrosis.
cell.com