Water for ADPKD? Probably, yes
VE Torres - Journal of the American Society of Nephrology, 2006 - journals.lww.com
Since its early descriptions, an impaired urine-concentrat-ing capacity has been a common
feature of autosomal dominant polycystic kidney disease (ADPKD), even at early stages of
the disease. Sixty-three of 71 patients who were studied by Dalgaard (1) were unable to
concentrate the urine to a specific gravity 1022 during a concentration test. Eleven of 13
patients who had a mean GFR of 103 ml/min per 1.73 m2 and were studied by Martinez-
Maldonado et al.(2) were unable to concentrate the urine above 700 mOsm/kg after 24 h of …
feature of autosomal dominant polycystic kidney disease (ADPKD), even at early stages of
the disease. Sixty-three of 71 patients who were studied by Dalgaard (1) were unable to
concentrate the urine to a specific gravity 1022 during a concentration test. Eleven of 13
patients who had a mean GFR of 103 ml/min per 1.73 m2 and were studied by Martinez-
Maldonado et al.(2) were unable to concentrate the urine above 700 mOsm/kg after 24 h of …