[CITATION][C] Controlled-release vaccines-biodegradable polylactide/polyglycolide (PL/PG) microspheres as antigen vehicles

MT Aguado, PH Lambert - Immunobiology, 1992 - Elsevier
There is an urgent need for new and improved vaccines, given the broad goal of decreasing
mortality and morbidity due to infectious diseases in developing countries. Moreover, there
is a need for easier methods of vaccine delivery than those currently available (1). One
possible way of facilitating this task is to reduce the number of repeated administrations
required for long-term protection. The number of doses required for a vaccine to be effective
against an infectious organism is a critical factor in achieving the appropriate level of …