[HTML][HTML] Possible role of glial cell line-derived neurotrophic factor for predicting cognitive impairment in Parkinson's disease: a case-control study

MY Shi, CC Ma, FF Chen, XY Zhou, X Li… - Neural Regeneration …, 2021 - journals.lww.com
Glial cell line-derived neurotrophic factor (GDNF) plays an important role in the protection of
dopaminergic neurons, but there are few reports of the relationship between GDNF and its
precursors (α-pro-GDNF and β-pro-GDNF) and cognitive impairment in Parkinson's disease.
This study aimed to investigate the relationship between the serum levels of GDNF and its
precursors and cognitive impairment in Parkinson's disease, and to assess their potential as
a diagnostic marker. Fifty-three primary outpatients and hospitalized patients with …