A review of the sheep-multiple sclerosis connection

TGC Murrell, PJ O'Donoghue, T Ellis - Medical hypotheses, 1986 - Elsevier
This paper reviews a notion that the prevalence of multiple sclerosis is high in global areas
where sheep populations are concentrated. Pilot studies are reported to serum antibodies in
humans to three sheep diseases; focal symmetrical encephalomalacia (FSE), maedi visna
and sarcocystis. In MS patients and controls antibodies were not found to the epsilon
neurotoxin of the FSE organism, Clostridium welchii type D and to a caprine retrovirus that is
closely related to maedi-visna virus. However, 34% of MS and control patients had …