Vaccines for measles, mumps, rubella, and varicella in children

C Di Pietrantonj, A Rivetti, P Marchione… - Cochrane Database …, 2020 - cochranelibrary.com
C Di Pietrantonj, A Rivetti, P Marchione, MG Debalini, V Demicheli
Cochrane Database of Systematic Reviews, 2020cochranelibrary.com
Background Measles, mumps, rubella, and varicella (chickenpox) are serious diseases that
can lead to serious complications, disability, and death. However, public debate over the
safety of the trivalent MMR vaccine and the resultant drop in vaccination coverage in several
countries persists, despite its almost universal use and accepted effectiveness. This is an
update of a review published in 2005 and updated in 2012. Objectives To assess the
effectiveness, safety, and long‐and short‐term adverse effects associated with the trivalent …
Background
Measles, mumps, rubella, and varicella (chickenpox) are serious diseases that can lead to serious complications, disability, and death. However, public debate over the safety of the trivalent MMR vaccine and the resultant drop in vaccination coverage in several countries persists, despite its almost universal use and accepted effectiveness. This is an update of a review published in 2005 and updated in 2012.
Objectives
To assess the effectiveness, safety, and long‐and short‐term adverse effects associated with the trivalent vaccine, containing measles, rubella, mumps strains (MMR), or concurrent administration of MMR vaccine and varicella vaccine (MMR+ V), or tetravalent vaccine containing measles, rubella, mumps, and varicella strains (MMRV), given to children aged up to 15 years.
cochranelibrary.com